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Medial collateral ligament (MCL) and lateral collateral ligament (LCL) sprains are knee injuries. The MCL is the ligament that’s located on the inside of your knee joint. It links your thighbone (e.g., femur) and shinbone (e.g., tibia). The LCL, on the other hand, is the ligament that’s located on the outside of your knee —linking the thighbone and calf bone (e.g., fibula). Similar to the medial collateral ligament (MCL), the LCL’s primary function is to stabilize side-to-side as the knee as it moves.